Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8566 | 8566 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T39E, S48T, A98S, K122E, D123N, I135T, E138A, I142IV, K173A, D177G, T200A, Q207D, R211K, V245Q |
| >8566| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSTNNATPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAQNPGIVIYQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, M36I, R41K, L63PT, H69K, T74TS, V77I, L89M, I93L |
| >8566| codons 5-99 LWQRPLVSIKVGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQITI EICGKKAIGSVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |