Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8990 | 8990 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | K101E, G190A | K238KT | T39E, E53D, K122E, D123S, I135T, A158S, K173A, Q174K, D177E, I178M, G196K, T200E, Q207E, R211K, L228Q, V245Q |
| >8990| codons 38-247 CEEMEKEGKISKIGPDNPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP SIFQSSMTKILEPFRAKNPEMVIYQYVDDLYVASDLEIKQHREKIEELREHLLKWGFTTP DQKHQKEPPFQWMGYELHPDTWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14N, L19T, K20R, M36I, L63V, H69K, L89M, I93L |
| >8990| codons 4-99 TLWQRPLVTINIGGQTREALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQIV IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |