<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
8990 8990 Malawi 2007 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V K219Q K101E, G190A K238KT T39E, E53D, K122E, D123S, I135T, A158S, K173A, Q174K, D177E, I178M, G196K, T200E, Q207E, R211K, L228Q, V245Q  
>8990| codons 38-247
CEEMEKEGKISKIGPDNPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLEKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRAKNPEMVIYQYVDDLYVASDLEIKQHREKIEELREHLLKWGFTTP
DQKHQKEPPFQWMGYELHPDTWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14N, L19T, K20R, M36I, L63V, H69K, L89M, I93L  
>8990| codons 4-99
TLWQRPLVTINIGGQTREALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQIV
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009