Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8760 | 8760 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, T69~, K70R, Q151M | V75I, F77L, F116Y | Y181I | T39E, E53D, S68G, K122E, D123S, I132L, S162Q, K173T, T200A, Q207GR, V245EK | P157A |
| >8760| codons 38-247 CEEMEKEGKISKIGPDNPYNTPVFAIKRKDG~RWRKLIDLRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYYSVPLDESFRKYTAFTLPSINNETPGIRYQYNVLPMGWKGSA AIFQQSMTKILEPFRTQNPDIVIIQYMDDLYVGSDLEIGQHRAKIEELRRHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20M, E35D, M36I, L63P, H69K, V82I, L89M, I93L |
| >8760| codons 4-99 TLWQRPLVSIKVGGQIMEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |