<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
8760 8760 Malawi 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, T69~, K70R, Q151M V75I, F77L, F116Y Y181I   T39E, E53D, S68G, K122E, D123S, I132L, S162Q, K173T, T200A, Q207GR, V245EK P157A
>8760| codons 38-247
CEEMEKEGKISKIGPDNPYNTPVFAIKRKDG~RWRKLIDLRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYYSVPLDESFRKYTAFTLPSINNETPGIRYQYNVLPMGWKGSA
AIFQQSMTKILEPFRTQNPDIVIIQYMDDLYVGSDLEIGQHRAKIEELRRHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIKLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20M, E35D, M36I, L63P, H69K, V82I, L89M, I93L  
>8760| codons 4-99
TLWQRPLVSIKVGGQIMEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009