Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8269 | 8269 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I15V, L19I, M36I, N37T, R41K, H69K, L89M, I93L |
| >8269| codons 4-99 TLWQRPVVTIKVGGQIKEALLDTGADDTVLEEITLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | A62V, V75I | V106M, Y181C, G190A | T39E, S48T, K122E, K173A, D177E, G196V, T200A, I202IV, E204K, Q207E, V245Q |
| >8269| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFVIKRKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHP AGLKKKKSMTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAQNPEIVICQYMDDLYVASDLEIVQHRAKVEKLREHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |