Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8015 | 8015 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | Y181C | K122E, I135R, I142V, T165M, K173A, Q174K, D177E, I195L, G196M, T200A, I202V, Q207E, R211IK, D218DE, V245Q |
| >8015| codons 40-247 EMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSRNNETPGVRYQYNVLPQGWKGSPAI FQSSMMKILEPFRAKNPEIVICQYVDDLYVGSDLELMQHRAKVEELREHLLKWGFTTPEK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, L19I, M36I, R41K, H69K, L89M, I93L |
| >8015| codons 4-99 TLWQRPLVTIRVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |