Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7344 | 7344 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70E, V75T, Q151M, M184V | A62V | K101E, Y181C, G190A | T39E, E40K, S48T, K104R, K122E, D123N, K173T, Q174R, I178L, T200A, Q207E, R211K, F214L, L228H, V245K |
| >7344| codons 38-247 CEKMEKEGKITKIGPENPYNTPVFVIKKKDSTEWRKLTDFRELNKRTQDFWEVQLGIPHP AGLEKKRSVTVLDVGDAYFSVPLDENFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRTRNPDLVICQYVDDLYVASDLEIGQHRAKIEELREHLLKWGLTTP DKKHQKEPPFHWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, K20R, M36I, R41K, D60E, Q61E, I62V, L63P, H69K, V77I, V82VI, L89M, I93L |
| >7344| codons 4-99 TLWQRPLVSIKVGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYEEVP IEICGKKAIGTVLIGPTPINIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |