<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
7344 7344 Malawi 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70E, V75T, Q151M, M184V A62V K101E, Y181C, G190A   T39E, E40K, S48T, K104R, K122E, D123N, K173T, Q174R, I178L, T200A, Q207E, R211K, F214L, L228H, V245K  
>7344| codons 38-247
CEKMEKEGKITKIGPENPYNTPVFVIKKKDSTEWRKLTDFRELNKRTQDFWEVQLGIPHP
AGLEKKRSVTVLDVGDAYFSVPLDENFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRTRNPDLVICQYVDDLYVASDLEIGQHRAKIEELREHLLKWGLTTP
DKKHQKEPPFHWMGYELHPDKWTVQPIKLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, K20R, M36I, R41K, D60E, Q61E, I62V, L63P, H69K, V77I, V82VI, L89M, I93L  
>7344| codons 4-99
TLWQRPLVSIKVGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYEEVP
IEICGKKAIGTVLIGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Hosseinipour, MC The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS, 2009