Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7241 | 7241 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, T69D, L74LV, M184V, L210W, T215Y | K219R | K103N | K238T | T39E, E44ED, V60I, V118I, K122E, D123N, I135LM, E138A, E169EA, F171Y, K173A, I195IT, T200A, I202V, Q207D, R211K, L228H, P243T, V245Q |
| >7241| codons 38-247 CEELEKDGKISKIGPENPYNTPIFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSMNNATPGIRYQYNVLPQGWKGSP AIFQSSMTKILAPYRAQNPDIVIYQYVDDLYVGSDLETGQHRAKVEELRDHLWKWGFYTP DRKHQKEPPFHWMGYELHPDTWTVQTIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36I, R41K, H69K, T74S, L89M, I93L |
| >7241| codons 4-99 TLWQRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |