Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8131 | 8131 | Malawi | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, L74I, M184V, T215F | D67G, V75S, K219E | Y181C | A98G, V108I | T39E, S48T, S68G, K122E, I135T, S162Y, K173T, V179I, G196E, T200A, E203K, Q207E, L210F, R211K, D218DE, K223KE, L228H, Q242H, V245X |
| >8131| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKGGTRWRKISDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTILDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRTQNPDIIICQYVDDLYVGSDLEIEQHRAKIKELREHLFKWGFFTP EEKHQEEPPFHWMGYELHPDKWTVHPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, R41K, D60E, Q61E, L63P, H69K, V77I, L89M, I93L |
| >8131| codons 4-99 TLWQRPLVSIKVGGQTKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYEEIP IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |