Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7081 | 7081 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | K219Q | K103N, Y181C | T39E, S48T, T69N, K122E, D123S, I135T, K173T, T200A, L228H, V245Q |
| >7081| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRTQNPDIVICQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTP DQKHQKEPPFHWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36L, N37S, R41K, H69K, K70KR, I72IM, L89M, I93L |
| >7081| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKRAMGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |