Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 9446 | 9446 | Malawi | 2007 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20KR, M36L, N37S, R41K, L63P, H69K, V77VI, L89M, I93L | Q58Q* |
| >9446| codons 4-99 TLWQRPLVSIKVGGQIREALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVR*YDQIP IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K103N | T39E, S48T, V90I, K122E, D123DG, I135IMT, S162H, K173IT, Q174K, D177E, I178IM, T200AE, E203ED, Q207E, R211KT, V245Q |
| >9446| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQHSMTKILEPFRTKNPEMVIYQYVDDLYVGSDLEIGQHREKIDELREHLLTWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Hosseinipour, MC | The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. | AIDS, 2009 |