Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5278 | CA12986 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 53 |
| 2 | DDI | 75 |
| 3 | DDC | 113 |
| 4 | 3TC+DDC+IDV | 185 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A | L24I | L10IV, I13V, K14KR, I15IL, L63P |
| >CA12986| codons 10-99 VVTVRLGGQLKEALIDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIPIEICGH KAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151KM, M184V | A62V | K20R, S68ST, F87FL, K122E, I135T, S162CW, F214L | G155GR, I159IL |
| >CA12941| codons 1-243 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKDTTKWRKLVDFRELNKRTQDLWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKRSPALFQWSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQP |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |