<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
92UG038 92UG038 Uganda 1992 HIV1 D PBMC Cons

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16E, K20R, M36I, R41K, H69Y, I72V  
>92UG038| codons 5-99
LWQRPLVTIKIEGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQILI
EICGYKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V108I E6K, K20R, V35T, K43R, V60I, K122E, D177E, I178M, Q207E, R211K, V245Q, D250E, A272P, K277S, T286A, I293V, E297K  
>92UG038| codons 1-297
PISPIKTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVSQLCKLLRGAKALTEVVPLTK

References
Author Title Citation
Cornelissen, M Pol diversity of five HIV-1 subtypes: Evidence for naturally occurring mutations that contribute to drug resistance, limited recombination patterns, and common ancestry for subtypes B and D. J Virol, 1997