Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TCDD-08 | TC08_2003 | Zimbabwe | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+SQV | 210 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72T, T74S, L89M, I93L |
| >TC08_2003| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QITIEICGKKATGSVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74LV, M184V | M230ML | V8I, K20R, V35K, E36A, T39E, S48T, V60I, K103KR, K173T, D177E, T200A, Q207E, T240TR | P97PA, K238KEGR |
| >TC08_2003| codons 1-253 PISPIETIPVKLKPGMDGPRVKQWPLTEEKIKALKAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHAAGLKKRKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWLGYELHPDRWR VQPIVLPEKDSWT |
References
| Author | Title | Citation |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |