Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TCDD-23 | TC23_2003 | Zimbabwe | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV+ DDC+ AZT | 304 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I15V, L19I, K20M, M36I, R41K, D60E, L63P, H69Q, V82I, L89M, I93L |
| >TC23_2003| codons 1-99 PQITLWQRPLVTIKVGGQIMEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QIPIEICGQKAIGTVLVGPTPINIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69T_T, K70R | D67G, K219Q | V35T, T39E, S48T, V60I, K64N, K103KR, V118I, K122E, D123S, E138A, T139A, K173T, Q174K, T200A, I202V, E203K, Q207E, R211K, F214L, D218E, L228HR, V245E, E248D |
| >TC23_2003| codons 1-253 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAINKKGSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSINNAAPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI YQYMDDLYVGSDLEIGQHRAKVKELREHLLKWGLTTPEQKHQKEPPFRWMGYELHPDKWT VQPIELPDKDSWT |
References
| Author | Title | Citation |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |