Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TC-68 | TC68_2004 | Zimbabwe | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | 61 |
| 2 | 3TC+AZT+NFV | 13 |
| 3 | 3TC+AZT+LPV | 4 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L, L90LM | L10LF | I15V, L19I, K20T, E35DG, M36I, N37S, R41K, I64L, H69K, V82I, I85V, L89M, I93L |
| >TC68_2004| codons 1-99 PQITLWQRPFVTIKVGGQITEALLDTGADDTVLEGISLPGKWKPKMIGGIGGFLKVRQYD QILLEICGKKAIGTVLVGPTPINIVGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K22R, I31L, V35T, E36A, T39E, E40D, S48T, T69A, W88C, K122E, D123S, S162H, K173A, D177E, E203Q, Q207E, R211K |
| >TC68_2004| codons 1-239 PISPIETVPVKLKPGMDGPKVRQWPLTEEKLKALTAICEDMEKEGKITKIGPENPYNTPV FAIKKKDSAKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRTKIQELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKW |
References
| Author | Title | Citation |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |