Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TC-68 | TC68_2003 | Zimbabwe | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | 21 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36I, N37S, R41K, I64L, H69K, V82I, L89M, I93L |
| >TC68_2003| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QILLEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106VM | K238KN | K22R, V35T, E36A, T39E, E40D, S48ST, T69A, W88C, K122E, D123NS, S162H, K173A, D177E, E203Q, Q207E, R211K, V245Q | H198HL |
| >TC68_2003| codons 1-253 PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALTAICEDMEKEGKITKIGPENPYNTPV FAIKKKDSAKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIGQLRTKIQELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDNWT VQPIQLPEKDSWT |
References
| Author | Title | Citation |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |