Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TCDD-13 | TC13_2003 | Zimbabwe | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 13 |
| 2 | 3TC+AZT+SQV | 69 |
| 3 | 3TC+AZT+NFV | 109 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19LI, M36I, R41K, L63V, H69K, V82I, I93L |
| >TC13_2003| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGTVLVGPTPINIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V35T, T39E, S48T, K49KE, K122E, D123S, E138A, K173V, Q174K, D177E, T200A, Q207A, P243T, V245Q | Y144YC |
| >TC13_2003| codons 1-253 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITEIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNATPGIRCQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQTIQLPEKDSWT |
References
| Author | Title | Citation |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |