Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TCDD-28 | TC28_2004 | Zimbabwe | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+SQV | 361 |
| 2 | 3TC+D4T+NVP | 57 |
| 3 | LPV+TDF | 17 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | K101E, Y181C, G190A | V35T, T39E, S48T, V60I, T69N, K122E, D123G, I135T, E138A, I167V, K173A, Q174K, N175Y, T200A, I202V, Q207A, H221Y |
| >TC28_2004| codons 1-243 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKVLEPFRAKYPDIVI CQYMDDLYVASDLEIGQHRAKVEELRAHLLRWGFFTPDQKYQKEPPFLWMGYELHPDKWT VQP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | G73S | I15V, L19I, K20I, M36I, L63P, H69K, A71V, I93L |
| >TC28_2004| codons 1-99 PQITLWQRPLVTIKVGGQIIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFIKVRQYD QIPIEICGKKVISTVLVGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |