Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TC-47 | TC47_2004 | Zimbabwe | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+NVP | 52 |
| 2 | 3TC+D4T+NVP | 30 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19T, M36I, R41K, I62V, L63S, H69K, A71T, I72E, I93L |
| >TC47_2004| codons 1-99 PQITLWQRPLVTIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QVSIEICGKKTEGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | F116Y | K103N, Y181C | K20R, V35T, E36A, T39E, E40D, S48T, S68G, K122E, D123E, S162A, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, H221HY, Q242QH |
| >TC47_2004| codons 1-242 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEDMEKEGKITKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQASMTKILEPFRAKNPELVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKYQKEPPFLWMGYELHPDKWT VH |
References
| Author | Title | Citation |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |