Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TC-41 | TC41_2004 | Zimbabwe | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 104 |
| 2 | 3TC+AZT+NVP | 70 |
| 3 | 3TC+D4T+NVP | 30 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70R, Y115F, Q151M, M184I | A62V, V75I, F77L, F116Y, K219E | Y181C | V35T, T39E, S68G, V118I, K122E, D123S, I142T, K173T, Q174K, T200A, Q207E, R211K, F214L, D218E |
| >TC41_2004| codons 1-243 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV FVIKRKDGTRWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFYSIPL DESFRKYTAFTIPSINNETPGTRYQYNVLPMGWKGSPAIFQSSMTKILEPFRTKNPDIVI CQYIDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPEEKHQKEPPFLWMGYELHPDKWT VQP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, G17D, L19I, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89M, I93L |
| >TC41_2004| codons 1-99 PQITLWQRPLVTIKVGDQIKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |