Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 134 | 134 | Japan | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | R41K, D60E, I62V, L63P, I93L |
| >134| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYE QVPIEICGHKAIGTVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E53ED, S68G, K122KQ, D123DE, D177E, G196E, R211G, V245E, A272P, V276I, L283LI, T286A, P294Q, Q334M, M357I, G359S, A371V, I375V, T377K, V381I, T403M, D460N, V467I, T470A, L491S, K512N, L517V, K558R |
| >134| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPDNPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DQEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIEQHRTKIEELRQHLLGWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLIRGAKALTEVIQLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGMGQWTYQIYQEPFKNLKTGKYARIRSA HTNDVKQLTEVVQKVAKESIIIWGKTPKFKLPIQKETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVISLADTTNQKTELQ AIHLALQDSGSEVNIVTDSQYALGIIQAQPDNSESEVVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRRVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| F100FC, K111T, T124A, T125A, I135V, I203M | S283G |
| >134| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYCLLKLAGRWPVTTIHTDNGSN FTSAAVKAACWWAGVKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Ibe, S | Analysis of near full-length genomic sequences of drug-resistant HIV-1 spreading among therapy-naive individuals in Nagoya, Japan: amino acid mutations associated with viral replication activity. | ARHR, 2008 |