<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E S283G
>314-40| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYVEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDMQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK
LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, I13V, L19I, K20I, E35D, M36I, N37S, R41K, C67S, H69K, V82I, L89M  
>314-40| codons 1-99
PQITLWQRPLVPVKIGGQIIEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVRQYD
QILIEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, V60VI, K122E, D123G, S162C, K173KR, Q174K, D177E, T200A, Q207E, R211S, V245Q, E248D, A272P, K275Q, V276T, E291D, V292I, I293V, T296TS, E297A, Q334L, F346Y, R356K, M357R, R358G, G359S, T377TI, K390KR, Q394R, A400V, E404D, Q428R, K431T, V435P, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, H483Q, L491S, K512R, S519N, A554S  
>314-40| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRRKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIQTKQLCKLLRGTKALTDIVPLSAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTEAVQKIAIESIVIWGKTPKFRLPIRKETWEVWWTDYWQATWIPEWEFVNTP
PLVKLWYRLETEPIPGAETYYVDGAANRETKLGKAGYVTDKGKQKIITLTETTNQKTELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Yamaguchi, J HIV type 1 group M subtype G in Cameroon: Five genome sequences. ARHR, 2009