<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CY112 CY112 Cyprus 2005 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14N, G16E, L19V, K20R, E35D, M36I, R41K, L63V, H69Q, L89M, Q92QH, I93M  
>CY112| codons 1-99
PQITLWQRPIVTVNIEGQVREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIVIEICGQKAIGTVLVGPTPVNIIGRNMLTHMGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11A, V35T, K122E, D123N, I135T, I142V, E169D, K173T, Q174K, D177E, T200A, Q207A, V245VEKM, T286A, V292I, I293V, P294T, A327V E248NY
>CY112| codons 1-334
PISPIETVPVALKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPYKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIVEIQKQGQ

References
Author Title Citation
Kousiappa, I Genetic analysis of HIV type 1 strains from newly infected untreated patients in Cyprus: high genetic diversity and low prevalence of drug resistance. ARHR, 2009