<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TMS314 TMS314 Tanzania 2005 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 NVP NA
2 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T4TA, I13V, K20R, E35D, M36I, P39PQ, R41K, K45R, R57K, L63P, H69K, L89M  
>TMS314| codons 1-99
PQIALWQRPLVTVKIGGQLREALLDTGADDTVLEDINLQGKWKPRMIGGIGGFIKVKQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40ED, K49KR, V60I, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245K, D250E, K275Q, K277R, T286A, E291D, V292I, I293V, P294T, E312D, S322T, Q334P, M357K, G359T, A371V, I375V, A376N, T377M, W383G  
>TMS314| codons 1-385
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIII
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYAGIQVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPTKDLIAEIQKQGPGQWTYQIYQEPFKNLKTGKYARKRTA
HTNDVKQLTEVVQKVNMESIVIGGK

References
Author Title Citation
Nyombi, BM Diversity of human immunodeficiency virus type 1 subtypes in Kagera and Kilimanjaro regions, Tanzania. ARHR, 2008