<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TMS220 TMS220 Tanzania 2005 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, E35D, P39Q, R41K, D60E, L63P, I64V, H69K, A71T, V77I  
>TMS220| codons 1-99
PQITLWQRPVVTVKIGGQLKEALLDTGADDTVLEDMNLQGKWKPKMIGGIGGFIKVRQYE
QIPVEICGKKTIGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40D, K49R, V60I, D121Y, K122E, D123G, I142V, Q174R, D177E, I178M, T200R, E204D, Q207E, R211K, V245N, D250E, A272P, K277R, L282C, L283I, I293V, E297D, D320DN, I329L, G335D, P345Q, F346Y  
>TMS220| codons 1-350
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEGFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPEMVI
YQYMDDLYVGSDLEIGQHRRKIEDLREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPINLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIRGTKALTEVVPLTDEAE
LELAENREILKEPVHGVYYNPSKDLIAELQKQGQDQWTYQIYQEQYKNLK

References
Author Title Citation
Nyombi, BM Diversity of human immunodeficiency virus type 1 subtypes in Kagera and Kilimanjaro regions, Tanzania. ARHR, 2008