<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TMS111 TMS111 Tanzania 2005 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 NVP NA
2 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q7E, I15V, L19I, R41K, D60E, L63Q, I64V, I72V, V77I  
>TMS111| codons 1-99
PQITLWERPLVTIKVGGQIKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYE
QIQVEICGHKAVGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179D I5V, K11Q, V35T, K49R, V60I, K103KR, D121H, K122E, T139K, I142V, A158S, E169K, K173E, T200I, Q207E, R211K, V245K, D250E, A272T, L282C, L283I, T286A, I293V, G335D, P345Q, F346Y, K347R, R356K, M357L, G359S, A360T  
>TMS111| codons 1-364
PISPVETVPVQLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSINNEKPGVRYQYNVLPQGWKGSPSIFQSSMTKILKPFREQNPDIDI
YQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYTGIKVKQLCKCIRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEQYRNLKTGKYAKLRST
HTND

References
Author Title Citation
Nyombi, BM Diversity of human immunodeficiency virus type 1 subtypes in Kagera and Kilimanjaro regions, Tanzania. ARHR, 2008