<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TBK049 TBK049 Tanzania 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NVP NA
2 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I15V, L19I, N37K, R41N, D60E, H69K, V77I, L89M, I93L  
>TBK049| codons 1-99
PQITLWQRPVVTIKVGGQIKEALLDTGADDTVLEEMKLPGNWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6K, V35T, E36AT, T39E, E40D, S48T, K122E, D123S, K166Q, K173A, T200A, Q207K, R211G, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, G335E, F346H, R356K, G359T, T377Q  
>TBK049| codons 1-381
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTTICEDMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTQILEPFRAQNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRKHLLGWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQEQWTYQIYQEPHKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIAQESIV

References
Author Title Citation
Nyombi, BM Diversity of human immunodeficiency virus type 1 subtypes in Kagera and Kilimanjaro regions, Tanzania. ARHR, 2008