<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt047 Pt047 Central African Republic 2006 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA
2 3TC+D4T+IDV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, E35D, M36I, N37D, L63AS, H69K, I72V, L89M  
>Pt047| codons 1-99
PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVRQYD
QISIEICGKKAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR   K101E, Y181C, G190A   K11AT, V35L, S68SG, S105SA, D121HY, K122E, I135IV, K173A, Q174K, D177E, G196E, Q207A, R211N, L228LR, V245Q, E248DN, D250DE, K281R, T286A, E291D, I293V  
>Pt047| codons 1-333
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPV
FAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKAVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
CQYMDDLYVASDLEIEQHRTKIEELRAHLLNWGFTTPDKKHQKEPPFRWMGYELHPDKWT
VQPIQLPNKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Gody, JC High prevalence of antiretroviral drug resistance mutations in HIV-1 non-B subtype strains from African children receiving antiretroviral therapy regimen according to the 2006 revised WHO recommendations. JAIDS, 2008