Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR102 | 03ZA.DR102 | South Africa | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+RTV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M | A62AV, V75I, F77FL, F116Y | A33AV, V35T, T39E, S68SG, T69S, K122E, D123S, K173A, D177E, T200A, Q207E, R211K, V245Q, S251N, A272P, K275Q, K277R, T286A, E291D, V292I, I293V |
| >03ZA.DR102| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKVLTEICEEMEKEGKISKIGPENPYNTPV FVIKKKDGSKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDNWTVNDIQKLVGKLNWASQIYPGIQVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82L, L90M | I13IV, I15V, K20R, M36I, R41RK, L63LP, H69K, L89I |
| >03ZA.DR102| codons 1-99 PQITLWQRPLVTVKVGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGKKAIGTVLVGPTPLNIIGRNIMTQIGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |