Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR100 | 03ZA.DR100 | South Africa | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+RTV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | G16GE, L19E, K20R, E35D, M36I, R41K, H69K, L89I, I93L | I15E |
| >03ZA.DR100| codons 1-99 PQITLWQRPLVTIKEEGQEREALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVRQYD QILIEICGKKAIGTVLVGPTPANIIGRNILTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | E6A, M16L, V35T, T39E, S48T, K122E, K173A, Q174R, D177E, T200E, I202V, Q207A, R211K, P243T, V245Q, A272P, L279T, T286A, E291D, V292I, I293V, E297K, G333E, Q334H | K30M |
| >03ZA.DR100| codons 1-335 PISPIATVPVKLKPGLDGPKVKQWPLTEEMIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIVI YQYVDDLYVGSDLEIGQHREKVEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQTCKLLRGAKALTDIVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQEHG |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |