Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR94 | 03ZA.DR94 | South Africa | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | P225H | I31L, V35T, E36A, T39D, S48T, K122E, I135L, E138D, I142V, K173T, D177E, T200A, Q207E, R211K, V245Q, D250E, A272P, K275Q, K277R, Q278N, T286A, E291D, V292I, I293V, E297A |
| >03ZA.DR94| codons 30-333 KLKALTAICDEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWE VQLGIPHPAGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSLNNDTPGVRYQYNVL PQGWKGSPAIFQSSMTKILEPFRTQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHL LKWGFTTPDKKHQKEHPFLWMGYELHPDKWTVQPIQLPEKESWTVNDIQKLVGKLNWASQ IYPGIQVRNLCKLLRGAKALTDIVPLTAEAELELAENREILKEPVHGVYYDPSKDLIAEI QKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36I, N37S, R41K, H69K, L89M, I93L |
| >03ZA.DR94| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |