<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR94 03ZA.DR94 South Africa 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N P225H I31L, V35T, E36A, T39D, S48T, K122E, I135L, E138D, I142V, K173T, D177E, T200A, Q207E, R211K, V245Q, D250E, A272P, K275Q, K277R, Q278N, T286A, E291D, V292I, I293V, E297A  
>03ZA.DR94| codons 30-333
KLKALTAICDEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWE
VQLGIPHPAGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSLNNDTPGVRYQYNVL
PQGWKGSPAIFQSSMTKILEPFRTQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHL
LKWGFTTPDKKHQKEHPFLWMGYELHPDKWTVQPIQLPEKESWTVNDIQKLVGKLNWASQ
IYPGIQVRNLCKLLRGAKALTDIVPLTAEAELELAENREILKEPVHGVYYDPSKDLIAEI
QKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19I, M36I, N37S, R41K, H69K, L89M, I93L  
>03ZA.DR94| codons 1-99
PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008