Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR93 | 03ZA.DR93 | South Africa | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | NA |
| 2 | D4T+EFV+LPV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R | K219Q | V106M, G190GA | V179VD, F227FL | A33G, V35T, E36A, T39E, K101Q, K122E, D123N, K173A, D177E, Q197L, T200A, Q207E, L228H, V245Q, A272P, K277R, E291D, V292I, I293V, V317A |
| >03ZA.DR93| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKGLTAICEEMEKEGKISKIGPENPYNTPV FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSMTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIDI YQYMDDLYVASDLEIGLHRAKIEELREHLLRWGFTTPDQKHQKEPPLHWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L10R, T12S, G17D, L19T, K20M, M36I, R41K, K55KR, L63T, H69K, I72T, L89M, I93L |
| >03ZA.DR93| codons 1-99 PQITLWQRPRVSIKIGDQTMEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIRVRQYD QITIEICGKKATGTVLVGPTPVNIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |