<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR93 03ZA.DR93 South Africa 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+IDV NA
2 D4T+EFV+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L90M   L10R, T12S, G17D, L19T, K20M, M36I, R41K, K55KR, L63T, H69K, I72T, L89M, I93L  
>03ZA.DR93| codons 1-99
PQITLWQRPRVSIKIGDQTMEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIRVRQYD
QITIEICGKKATGTVLVGPTPVNIIGRNMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R K219Q V106M, G190GA V179VD, F227FL A33G, V35T, E36A, T39E, K101Q, K122E, D123N, K173A, D177E, Q197L, T200A, Q207E, L228H, V245Q, A272P, K277R, E291D, V292I, I293V, V317A  
>03ZA.DR93| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKGLTAICEEMEKEGKISKIGPENPYNTPV
FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIDI
YQYMDDLYVASDLEIGLHRAKIEELREHLLRWGFTTPDQKHQKEPPLHWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQG

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008