Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR84 | 03ZA.DR84 | South Africa | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y188L, G190A | V179D | V8I, V35K, T39E, S48E, V60I, K103R, I159V, K173T, Q174K, T200A, Q207E, R211K, V245Q, D250E, A272P, K277T, K281KR, T286A, V292I, I293V, E297K, L301F |
| >03ZA.DR84| codons 1-333 PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALKEICEEMEKEGKIEKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAVFQSSMTKILEPFRTKNPDIDI YQYMDDLLVASDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVTQLCRLLRGAKALTEIVPLTKEAE FELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12E, I15V, L19I, M36I, R41K, L63DV, I64M, H69K, I72V, L89M, I93L |
| >03ZA.DR84| codons 1-99 PQITLWQRPLVEIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIVMEICGKKAVGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |