<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR80 03ZA.DR80 South Africa 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+DDI+EFV NA
2 3TC+AZT+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12TS, I15V, L19IM, K20R, M36L, N37S, R41K, Q61N, L63S, H69K, V77I, L89M, I93L  
>03ZA.DR80| codons 1-99
PQITLWQRPLVSIKVGGQMREALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYD
NISIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N P225H V35T, T39E, S48T, K122E, D123G, K173A, Q174R, D177E, T200A, Q207A, L210F, R211K, V245Q, A272P, K277R, E291D, V292I, I293V  
>03ZA.DR80| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLFKWGFTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008