Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR80 | 03ZA.DR80 | South Africa | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+D4T+DDI+EFV | NA |
| 2 | 3TC+AZT+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TS, I15V, L19IM, K20R, M36L, N37S, R41K, Q61N, L63S, H69K, V77I, L89M, I93L |
| >03ZA.DR80| codons 1-99 PQITLWQRPLVSIKVGGQMREALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYD NISIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | P225H | V35T, T39E, S48T, K122E, D123G, K173A, Q174R, D177E, T200A, Q207A, L210F, R211K, V245Q, A272P, K277R, E291D, V292I, I293V |
| >03ZA.DR80| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLFKWGFTTPDKKHQKEHPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |