<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR79 03ZA.DR79 South Africa 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, K70KR, Q151LM V75VA K103N, V106M   S3SR, T27S, V35T, T39E, S48T, V60I, S68G, K73KM, K122E, D123N, I159V, D177E, I178L, T200A, E203EK, Q207D, R211K, V245Q, A272P, T286V, V292I, I293V, S322T, D324E I5IS, T7TFIS
>03ZA.DR79| codons 1-333
PIRPSESVPVKLKPGMDGPKVKQWPLSEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKRKDGTRWRMLADFRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAVFQSSMTKILEPFRKQNPELVI
YQYMDDLYVGSDLEIGQHRAKIKELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGVKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPTKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, R41K, L63P, H69K, K70KR, V77I, V82I, L89M, I93L  
>03ZA.DR79| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKRAIGTVLIGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008