Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR76 | 03ZA.DR76 | South Africa | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | K219Q | V35T, E36A, T39E, K64KN, K122E, D123DG, K173A, Q174K, D177E, I178L, T200A, Q207KN, L210LF, R211KM, V245Q, A272P, K277R, Q278H, T286A, I293V |
| >03ZA.DR76| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV FAINKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPELVI YQYMDDLYVGSDLEIGQHRAKIEELRNHLFMWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, Q18E, L19I, K20R, E35D, M36I, R41K, L63LV, H69K, T74S, L89M, I93L |
| >03ZA.DR76| codons 1-99 PQITLWQRPLVSIKVGGEIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |