Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR42 | 02ZA.DR42 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | NA |
| 2 | 3TC+AZT+IDV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82VA | T12S, I15V, L19I, E35ED, M36I, R41K, I62IV, L63V, H69K, T74A, L89M, I93L, N98I |
| >02ZA.DR42| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QVVIEICGKKAIGAVLVGPTPANIIGRNMLTQLGCTLIF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | T215TA | K32KR, V35T, E36EA, T39E, V60VI, D121Y, K122E, I135IL, K173KR, Q174K, P176T, D177G, T200A, I202IV, R211K, D250E, A272P, K277R, T286A, V292*, I293V, S322AE | Y115YN |
| >02ZA.DR42| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALTAICEEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDANFSVPL YEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNTGIVI YQYVDDLYVGSDLEIGQHRAKVEELRQHLLKWGFATPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTE*VPLTEEAE LELAENREILKEPVHGVYYDPEKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |