Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR31 | 02ZA.DR31 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101KE, G190A | V35T, E36A, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, I178M, T200A, Q207E, R211Q, V245Q, A272P, K277R, E291D, V292I, I293V, E297EA |
| >02ZA.DR31| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEMVI YQYVDDLYVASDLEIGQHRAKIEELREHLLQWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TS, G16E, L19I, R41K, L63V, H69K, V77I, L89M, I93L |
| >02ZA.DR31| codons 1-99 PQITLWQRPLVSIKIEGQIKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |