Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR30 | 02ZA.DR30 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | V35T, T39E, S48T, D121DE, K122E, D123S, A158S, S162N, E169A, K173E, I178IM, T200A, Q207E, V245Q, A272P, Q278N, T286A, E291D, V292I, I293V, D324E |
| >02ZA.DR30| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL EESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQNSMTKILAPFREQNPDMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKNLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, L63AV, H69K, T74S, L89M, I93L |
| >02ZA.DR30| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |