<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR27 02ZA.DR27 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41*LQ, M184V, T215Y   P236L A98G V35T, E36A, T39K, K43E, K122E, D123G, I135L, K173A, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248D, A272P, K277R, K281R, T286A, E291D, V292I  
>02ZA.DR27| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICKEQEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFYTPDKKHQKEPPFLWMGYELHLDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGAKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14N, I15V, L19T, N37NS, R41K, Q61QH, L63P, H69K, K70R, L89M V77VA
>02ZA.DR27| codons 1-99
PQITLWQRPLVTINVGGQTKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD
HIPIEICGKRAIGTVLAGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008