Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR27 | 02ZA.DR27 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41*LQ, M184V, T215Y | P236L | A98G | V35T, E36A, T39K, K43E, K122E, D123G, I135L, K173A, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248D, A272P, K277R, K281R, T286A, E291D, V292I |
| >02ZA.DR27| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICKEQEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFYTPDKKHQKEPPFLWMGYELHLDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14N, I15V, L19T, N37NS, R41K, Q61QH, L63P, H69K, K70R, L89M | V77VA |
| >02ZA.DR27| codons 1-99 PQITLWQRPLVTINVGGQTKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD HIPIEICGKRAIGTVLAGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |