Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR26 | 02ZA.DR26 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, V75T | A62V | I2V, V35T, T39E, S48T, E53D, S68G, V118I, K122E, D123S, I135T, E138A, E169ED, K173AT, Q174K, I178M, T200A, Q207E, R211RK, F214L, K219G, V245VE, D250E, A272P, K277R, L283I, T286A, E291D, V292I, I293V, V317A | K263KN |
| >02ZA.DR26| codons 1-333 PVSPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPDNPYNTPV FVIKRKDGTKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRTKNPDMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDGKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGNLNWASQIYPGIKVRQLCKLIRGAKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, M36I, R41K, K45R, D60E, L63LP, H69K, L89M, I93L |
| >02ZA.DR26| codons 9-99 PLVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPRMIGGIGGFIKVRQYEQIPIEICG KKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |