<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR23 02ZA.DR23 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+IDV+LPV+MKC442 NA
2 3TC+ABC+AZT NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V T215TI, K219Q K103S E138KQ K20KR, V35T, E36A, T39E, V60VI, K102R, K122E, D123G, I142K, S162A, K173T, Q174K, D177E, I178M, V179VI, T200A, Q207D, R211K, F214L, V245Q, A272P, K277KR, E291D, V292I, I293V, K311R, D324E  
>02ZA.DR23| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRSKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNQTPGKRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMII
YQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGLITPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILREPVHGVYYDPSKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16A, G17D, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
>02ZA.DR23| codons 1-99
PQITLWQRPLVSIKVADQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008