Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR19 | 02ZA.DR19 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69S_SS, L210W, T215Y | D67E | K101E, V106M, G190A | F227FL | V8VA, V35I, T39E, E53D, K122E, D123S, S162C, E169A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250DE, A272P, K277KR, E291D, V292VI |
| >02ZA.DR19| codons 1-333 PISPIETAPVKLKPGMDGPKVKQWPLTEEKIKALIEICEELEKEGKISKIGPDNPYNTPV FAIKKKESSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSMTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILAPFRTKNPEIVI YQYMDDLYVASDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPLLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L |
| >02ZA.DR19| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |