Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR18 | 02ZA.DR18 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, K70KR | V106M | V179D | E6EK, K20KR, V35T, T39E, K66E, L100LV, K102Q, K103R, K122E, I135IM, I142IV, K173T, T200A, E204Q, Q207E, F214L, V245Q, A272P, T286V, V292I, I293V, G333E, Q334H | S48IT, G51GW |
| >02ZA.DR18| codons 1-335 PISPIKTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITKIWPENPYNTPV FAIKKENSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGVKQRKSMTVLDVGDAYFSVPL DEDFRKYTAFTIPSMNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIDI YQYMDDLYVGSDLEIGQHRAKIEQLREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGVKALTEIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQEHG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, T74S, L89M, I93L |
| >02ZA.DR18| codons 1-99 PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |