Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5097 | CA12380 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | 61 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K102R, K122E, D123E, I142T, D177E, I178M, H208Y, T240TA, A272P, K281X, I293V |
| >CA12380| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYVDDLYVGSDLEIGQHRTKIEELRQYLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWA VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCXLLRGTKALTEVVPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L24I | E35D, M36I, R41K, D60E, I62V, L63P, I64V, I72V, V77I |
| >CA12579| codons 1-99 PQITLWQRPLVTIKIGGQLKEALIDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVRQYE QVPVEICGHKAVGTVLIGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |