Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8346 | CA123387 | U.S. | 2008 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+SQV | 39 |
| 2 | 3TC+D4T+IDV | 165 |
| 3 | 3TC+D4T+IDV+RTV | 156 |
| 4 | Unknown | 298 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54S, V82A | L33F, Q58E | L10I, I13IV, D60E, L63P, A71V, V77I, T91A |
| >CA123387| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEEMNLPGRWKPKMIVGIGGFSKVREYE QIPIEICGHKVIGTVLIGPTPANIIGRNLLAQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, M184V, L210W, T215Y | K219KN | P4S, A98S, V118I, K122E, D123E, I135V, K166R, R211K, I244IV, A272P, K277R, T286A, V292I, I293V, E297Q |
| >CA123388| codons 1-299 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSIPL DEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT VQPVVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEIVPLTQEA |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |