<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
97 5247096 Switzerland 2002 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 None NA
2 NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, N88S, L90M   K14R, E35D, M36V, R41K, I62V, L63P, G68E, A71V, I93L, L97F, N98K  
>5247096| codons 1-99
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEDVNLPGKWKPKLIGGIGGFIKVRQYD
QVPIEICEHKVIGTVLVGPTPVNIIGRSLMTQLGCTFKF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       D123E, I135T, S162C, Q174R, D177E, T200A, R211K  
>5247096| codons 29-224
EKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFW
EVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNV
LPQGWKGSPAIFQCSMTKILEPFRKRNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRQH
LLKWGFTTPDKKHQKE

References
Author Title Citation
von Wyl, V Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment: a comparison of different regimen types. Arch Intern Med, 2007