<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
112 1435894 Switzerland 2003 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA
2 NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       P4S, V35T, E36D, T39S, V90G, D121H, I132V, I135V, S162A, K173T, Q174K, D177E, V179I, T200A, E203K, Q207E E89G, Q91P, L92V
>1435894| codons 1-224
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICSEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWGGPVGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HKDFRKYTAFTVPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIII
YQYVDDLYVGSDLEIGQHRAKIKELREHLLRWGFTTPDKKHQKE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, N88S   I13V, K14R, K20I, E35G, M36I, N37D, R41K, H69K, V77I, L89M  
>1435894| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEGIDLPGKWKPKLIGGIGGFIKVRQYD
QILIEICGKKAIGTVLIGPTPVNIIGRSMLTQIGCTLNF

References
Author Title Citation
von Wyl, V Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment: a comparison of different regimen types. Arch Intern Med, 2007