<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
157 4818282 Switzerland 2002 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA
2 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   V35T, T39Q, V60I, K122E, D123G, I135T, K173E, D177E, G196E, Q207E  
>4818282| codons 1-224
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICQEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFREQNPEIVI
YQYVDDLYVGSDLEIEQHRTKIEELREHLLRWGFTTPDKKHQKE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, G17E, K20IL, E34K, M36L, N37D, R57K, Q61N, I62M, L63S, C67E, H69K, V77I, L89M  
>4818282| codons 1-99
PQITLWQRPLVTVRIGEQLLEALLDTGADDTVLKELDLPGRWKPKMIGGIGGFIKVKQYD
NMSIEIEGKKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
von Wyl, V Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment: a comparison of different regimen types. Arch Intern Med, 2007